Benazepril hydrochloride Drug Information

Contains Benazepril hydrochloride drug information and provides Benazepril hydrochloride drug indication, contraindication, special concerns, side effects, overdose management and dosage
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Indications:
Alone or in combination with thiazide diuretics to treat hypertension.
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Contraindications:
Hypersensitivity to benazepril or any other ACE inhibitor.
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Special Concerns:
Use with caution during lactation. Safety and effectiveness have not been determined in children.
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Side Effects:
CNS: Headache, dizziness, fatigue, anxiety, insomnia, drowsiness, nervousness. GI: N&V, constipation, abdominal pain, gastritis, melena, pancreatitis. CV: Symptomatic hypotension, postural hypotension, syncope, angina pectoris, palpitations, peripheral edema, ECG changes. Dermatologic: Flushing, photosensitivity, pruritus, rash, diaphoresis. GU: Decreased libido, impotence, UTI. Respiratory: Cough, asthma, bronchitis, dyspnea, sinusitis, bronchospasm. Neuromuscular: Paresthesias, arthralgia, arthritis, asthenia, myalgia. Hematologic: Occasionally, eosinophilia, leukopenia, neutropenia, decreased hemoglobin. Miscellaneous: Angioedema, which may be associated with involvement of the tongue, glottis, or larynx; hypertonia; proteinuria; hyponatremia; infection.
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Overdose Management:
No Available information
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Drug Interactions:
Diuretics / Excessive in BP Lithium / Serum lithium levels with risk of lithium toxicity Potassium-sparing diuretics, potassium supplements / Risk of hyperkalemia
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Dosage:
•Tablets Clients not receiving a diuretic.

Initial: 10 mg once daily; maintenance: 20-40 mg/day given as a single dose or in two equally divided doses. Total daily doses greater than 80 mg have not been evaluated.

Clients receiving a diuretic.

Initial: 5 mg/day.



CCR < 30 mL/min/1.73 m2. The recommended starting dose is 5 mg/day; maintenance: titrate dose upward until BP is controlled or to a maximum total daily dose of 40 mg.
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