Bisoprolol fumarate and Hydrochlorothiazide Drug Information
Contains Bisoprolol fumarate and Hydrochlorothiazide drug information and provides Bisoprolol fumarate and Hydrochlorothiazide drug indication, contraindication, special concerns, side effects, overdose management and dosage
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Indications:
First-line therapy in mild to moderate hypertension
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Contraindications:
Use in bronchospastic pulmonary disease, cardiogenic shock, overt CHF, second- or third-degree AV block, marked sinus bradycardia, anuria, hypersensitivity to either drug or to other sulfonamide-derived drugs, during lactation.
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Special Concerns:
Use with caution in clients with peripheral vascular disease, impaired renal or hepatic function, and progressive liver disease and in clients also receiving myocardial depressants or inhibitors of AV conduction such as verapamil, diltiazem, and disopyramide. Elderly clients may be more sensitive to the effects of this drug product. Safety and effectiveness have not been determined in children.
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Side Effects:
See individual drugs. Most commonly, dizziness and fatigue. At higher doses, bisoprolol inhibits beta-2-adrenergic receptors located in bronchial and vascular muscle.
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Overdose Management:
No Available information
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Drug Interactions:
Antihypertensives / Additive effect to decrease BP Cyclopropane / Additive depression of myocardium Trichloroethylene / Additive depression of myocardium
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Dosage:
•Tablets Antihypertensive.

Adults, initial: One 2.5/6.25-mg tablet given once daily. If needed, the dose may be increased q 14 days to a maximum of two 10/6.25-mg tablets given once daily.
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