Kanamycin sulfate[ (Kantrex) ] Drug Information

Contains Kanamycin sulfate drug information and provides Kanamycin sulfate drug indication, contraindication, special concerns, side effects, overdose management and dosage
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List of Contents:
  • Indications
  • Contraindications
  • Special Concerns
  • Side Effects
  • Overdose Management
  • Dosage

  • Indications:
    Parenteral: Initial therapy for infections due to Escherichia coli, Proteus, Enterobacter aerogenes, Klebsiella pneumoniae, Serratia marcescens and Acinetobacter. May be combined with a penicillin or cephalosporin before knowing results of susceptibility tests. Investigational: As part of a multiple-drug regimen for Mycobacterium avium complex in AIDS clients.

    PO: Adjunct to mechanical cleansing of large bowel for suppression of intestinal bacteria; hepatic coma.
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    Contraindications:
    No Available information
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    Special Concerns:
    : Use with caution in premature infants and neonates.
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    Side Effects:
    Sprue-like syndrome with steatorrhea, malabsorption, and electrolyte imbalance.
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    Overdose Management:
    No Available information
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    Drug Interactions:
    Procainamide muscle relaxation.
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    Dosage:
    Capsules Intestinal bacteria suppression.

    1 g every hour for 4 hr; then, 1 g q 6 hr for 36-72 hr.

    Hepatic coma.

    8-12 g/day in divided doses.

    IM, IV

    Adults and children: 15 mg/kg/day in two to three equal doses. Maximum daily dose should not exceed 1.5 g regardless of route of administration.

    For calculating dosage interval (in hr) in clients with impaired renal function, multiply serum creatinine (mg/100 mL) by 9.

    IM Tuberculosis.

    Adults: 15 mg/kg/day. Not recommended for use in children.

    Intraperitoneal

    500 mg diluted in 20 mL sterile distilled water.

    Inhalation

    250 mg in saline--nebulize b.i.d.-q.i.d.

    Irrigation of abscess cavities, pleural space, ventricular cavities.

    0.25% solution.
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