Lorazepam[ (Ativan) ] Drug Information

Contains Lorazepam drug information and provides Lorazepam drug indication, contraindication, special concerns, side effects, overdose management and dosage
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Indications:
PO: Anxiety, tension, anxiety with depression, insomnia, acute alcohol withdrawal symptoms. Parenteral: Amnesic agent, anticonvulsant, antitremor drug, adjunct to skeletal muscle relaxants, preanesthetic medication, adjunct prior to endoscopic procedures, treatment of status epilepticus, relief of acute alcohol withdrawal symptoms. Investigational: Antiemetic in cancer chemotherapy.
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Contraindications:
Narrow-angle glaucoma. Parenterally in children less than 18 years
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Special Concerns:
PO dosage has not been established in children less than 12 years of age and IV dosage has not been established in children less than 18 years of age. Use cautiously in presence of renal and hepatic disease.
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Side Effects:
No Available information
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Overdose Management:
No Available information
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Drug Interactions:
With parenteral lorazepam, scopolamine sedation, hallucinations, and behavioral abnormalities.
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Dosage:
•Tablets, Concentrate Anxiety.

Adults: 1-3 mg b.i.d.-t.i.d.

Hypnotic.

Adults: 2-4 mg at bedtime. Geriatric/debilitated clients, initial: 0.5-2 mg/day in divided doses. Dose can be adjusted as required.

•IM Preoperatively.

Adults: 0.05 mg/kg up to maximum of 4 mg 2 hr before surgery for maximum amnesic effect.

•IV Preoperatively.

Adults, initial: 0.044 mg/kg or a total dose of 2 mg, whichever is less.

Amnesic effect.

Adults: 0.05 mg/kg up to a maximum of 4 mg administered 15-20 min prior to surgery.

Antiemetic in cancer chemotherapy.

Initial: 2 mg 30 min before beginning chemotherapy; then, 2 mg q 4 hr as needed.
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