Sulfadiazine[ (Microsulfon) ] Drug Information

Contains Sulfadiazine drug information and provides Sulfadiazine drug indication, contraindication, special concerns, side effects, overdose management and dosage
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Indications:
UTIs caused by Escherichia coli, Klebsiella Enterobacter Staphylococcus aureus, Proteus mirabilis, and Proteus vulgaris. Chancroid, inclusion conjunctivitis, adjunct in treating chloroquine-resistant strains of Plasmodium falciparum meningitis caused by Haemophilus influenzae, meningococcal meningitis for sulfonamide-sensitive group A strains, nocardiosis, with penicillin to treat acute otitis media caused by H. influenzae rheumatic fever prophylaxis, adjunct with pyrimethamine for toxoplasmosis in selected immunocompromised clients (e.g., those with AIDS, neoplastic disease, or congenital immune compromise), trachoma.
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Contraindications:
Use in infants less than 2 months of age unless combined with pyrimethamine to treat congenital toxoplasmosis.
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Special Concerns:
Safe use during pregnancy has not been established.
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Side Effects:
No Available information
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Overdose Management:
No Available information
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Drug Interactions:
No Available information
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Dosage:
•Tablets General use.

Adults, loading dose: 2-4 g; maintenance: 2-4 g/day in 3 to 6 divided doses; infants over 2 months, loading dose: 75 mg/kg/day (2 g/m2); maintenance: 150 mg/kg/day (4 g/m2/day) in 4 to 6 divided doses, not to exceed 6 g/day.

Rheumatic fever prophylaxis.

Under 30 kg: 0.5 g/day; over 30 kg: 1 g/day.

As adjunct with pyrimethamine in congenital toxoplasmosis.

Infants less than 2 months: 25 mg/kg q.i.d. for 3 to 4 weeks. Children greater than 2 months: 25-50 mg/kg q.i.d. for 3 to 4 weeks.
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