Ferrous sulfate[ (Feosol) ] Drug Information

Contains Ferrous sulfate drug information and provides Ferrous sulfate drug indication, contraindication, special concerns, side effects, overdose management and dosage
Search Drugs by Generic or Trade Name:
Browse Drugs by Generic Name:
[ A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z ]


Indications:
Prophylaxis and treatment of iron deficiency and iron-deficiency anemias. Dietary supplement for iron. Optimum therapeutic responses are usually noted within 2-4 weeks. Investigational: Clients receiving epoetin therapy (failure to give iron supplements either IV or PO can impair the hematologic response to epoetin).
Back to Top
Contraindications:
Hemosiderosis, hemochromatosis, peptic ulcer, regional enteritis, and ulcerative colitis. Hemolytic anemia, pyridoxine-responsive anemia, and cirrhosis of the liver. Use in those with normal iron balance.
Back to Top
Special Concerns:
Allergic reactions may result due to certain products containing tartrazine and some products containing sulfites.
Back to Top
Side Effects:
GI: Constipation, gastric irritation, nausea, abdominal cramps, anorexia, vomiting, diarrhea, dark-colored stools. These effects may be minimized by administering preparations as a coated tablet. Soluble iron preparations may stain the teeth.
Back to Top
Overdose Management:
Symptoms: Symptoms occur in four stages--(1) Lethargy, N&V, abdominal pain, weak and rapid pulse, tarry stools, dehydration, acidosis, hypotension, and coma within 1-6 hr. (2) If client survives, symptoms subside for about 24 hr. (3) Within 24-48 hr symptoms return with diffuse vascular congestion, shock, pulmonary edema, acidosis, seizures, anuria, hyperthermia, and death. (4) If client survives, pyloric or antral stenosis, hepatic cirrhosis, and CNS damage are seen within 2-6 weeks. Toxic reactions are more likely to occur after parenteral administration.Treatment (Iron Toxicity): General supportive measures. Maintain a patent airway, respiration, and circulation. Induce vomiting with syrup of ipecac followed by gastric lavage using tepid water or 1%-5% sodium bicarbonate (to convert from ferrous sulfate to ferrous carbonate, which is poorly absorbed and less irritating). Saline cathartics can also be used. Deferoxamine is indicated for clients with serum iron levels greater than 300 mg/dL. Deferoxamine is usually given IM, but in severe cases of poisoning it may be given IV. Hydration should be maintained. It may be necessary to treat for shock, acidosis, renal failure, and seizures.
Back to Top
Drug Interactions:
Antacids, oral / Iron absorption from GI tract Ascorbic acid / Ascorbic acid, 200 mg or more, iron absorption Chloramphenicol / Serum iron levels Cholestyramine / Iron absoprtion from GI tract Cimetidine / Iron absorption from GI tract Fluoroquinolones / Fluoroquinolone absorption from GI tract R/T formation of a ferric ion-quinolone complex Levodopa / Levodopa absorption R/T formation of chelates with iron salts Levothyroxine / Levothyroxine efficacy Methyldopa / Methyldopa absorption from GI tract Pancreatic extracts / Iron absorption from GI tract Penicillamine / Penicillamine absorption from GI tract due to chelation St. John's wort / May absorption of iron Tetracyclines / Absorption of both tetracyclines and iron from GI tract Vitamin E / Response to iron therapy
Back to Top
Dosage:
Ferrous Sulfate •Extended-Release Capsules

Adults: 150-250 mg 1-2 times/day. This dosage form is not recommended for children.

•Elixir, Oral Solution, Tablets, Enteric-coated Tablets Prophylaxis.

Adults: 300 mg/day. Pediatric: 5 mg/kg/day.

Anemia.

Adults: 300 mg b.i.d. increased to 300 mg q.i.d. as needed and tolerated. Pediatric: 10 mg/kg t.i.d. The enteric-coated tablets are not recommended for use in children.

•Extended-Release Tablets

Adults: 525 mg 1-2 times/day. This dosage form is not recommended for use in children.

Ferrous Sulfate, Dried •Capsules Prophylaxis.

Adults: 300 mg/day. Pediatric: 5 mg/kg/day.

Anemia.

Adults: 300 mg b.i.d. up to 300 mg q.i.d. as needed and tolerated. Pediatric: 10 mg/kg t.i.d.

•Tablets Prophylaxis.

Adults: 200 mg/day. Pediatric: 5 mg/kg/day.

Anemia.

Adults: 200 mg t.i.d. up to 200 mg q.i.d. as needed and tolerated. Pediatric: 10 mg/kg t.i.d.

•Extended-Release Tablets

Adults: 160 mg 1-2 times/day. This dosage form is not recommended for use in children.
Back to Top